Article
Characterization of 40 novel HLA class I and class II alleles identified in umbilical cord blood units.
HLA - 1 Jun 2023
Rajendran Sureka, Murugan Alagupandian, Nandakumar Yogesh, Chaturvedi Ankur, Phani Nagaraja M, Padhiar Chirayu, Goditala Pardhasaradhi, Gambhir Prakash Sadashiv
Abstract excerpt
Forty novel HLA class I and class II alleles were identified in umbilical cord blood (UCB) samples and categorized based on various types of mutations: non-synonymous, synonymous, frameshift, and premature termination codon. This study described 14 novel HLA-A alleles, 9 novel HLA-B alleles, 4 novel HLA-C alleles, 3 novel HLA-DRB1 alleles and 10 novel HLA-DQB1 alleles. Comparing the new allele sequence with the...
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