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Genetic Susceptibility to Mood Disorders and Risk of Stroke: A Polygenic Risk Score and Mendelian Randomization Study.

Stroke - 1 May 2023

Sun Jiangming, Borné Yan, Edsfeldt Andreas, Wang Yunpeng, Pan Mengyu, Melander Olle, Engström Gunnar, Gonçalves Isabel

Abstract excerpt

BACKGROUND: Mood disorders and strokes are often comorbid, and their health toll worldwide is huge. This study characterizes prognostic and causal roles of mood disorders in stroke. METHODS: We tested if genetic susceptibilities for mood disorders were associated with all strokes, ischemic strokes in the Malmö Diet and Cancer cohort (24 631 individuals with a median follow-up of 21.3 (interquartile range:...

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Identifiers

PMID: 36942587
DOI: 10.1161/STROKEAHA.122.041026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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