Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung versus thyroid lineage specification

1 Jan 2017

Abstract excerpt

The in vitro directed differentiation of pluripotent stem cells (PSCs) through stimulation of developmental signaling pathways can generate mature somatic cell types for basic laboratory studies or regenerative therapies. However, there has been significant uncertainty regarding how to separately derive lung vs. thyroid epithelial lineages, since these two cell types each originate from Nkx2-1+ foregut...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neonatal Respiratory Health Research
Share to Pluripotent Stem Cells Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28947536
DOI: 10.1242/dev.150193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung versus thyroid lineage specificationPMID 28947536Read ↗

Derivation of Epithelial‐Only Airway Organoids from Human Pluripotent Stem CellsSemantic proximity Read ↗

Embryonic and Induced Pluripotent Stem Cells for Lung RegenerationSemantic proximity Read ↗

Single cell transcriptomics reveals a signaling roadmap coordinating endoderm and mesoderm diversification during foregut organogenesisSemantic proximity Read ↗

β-Catenin maintains lung epithelial progenitors after lung specificationSemantic proximity Read ↗

Generation of Lung Epithelium from Pluripotent Stem CellsSemantic proximity Read ↗

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and DiseaseSemantic proximity Read ↗

Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cellsSemantic proximity Read ↗

A spatially-resolved blueprint of the developing human lung reveals a WNT-driven niche for basal stem cellsSemantic proximity Read ↗

Lung Endoderm Morphogenesis: Gasping for Form and FunctionSemantic proximity Read ↗

Lymphoid cell development from fetal hematopoietic progenitors and human pluripotent stem cellsSemantic proximity Read ↗

Single-cell time-series mapping of cell fate trajectories reveals an expanded developmental potential for human PSC-derived distal lung progenitorsSemantic proximity Read ↗

A Roadmap for Human Liver Differentiation from Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.