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Integration of stress signals by homeodomain interacting protein kinases

8 Nov 2013

Abstract excerpt

The family of homeodomain interacting protein kinases (HIPKs) consists of four related kinases, HIPK1 to HIPK4. These serine/threonine kinases are evolutionary conserved and derive from the yeast kinase Yak1. The largest group of HIPK phosphorylation substrates is represented by transcription factors and chromatin-associated regulators of gene expression, thus transferring HIPK-derived signals into changes of...

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PMID: 24225127
DOI: 10.1515/hsz-2013-0264

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