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Feline myocardial transcriptome in health and in hypertrophic cardiomyopathy—A translational animal model for human disease

16 Mar 2023

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats, characterized by primary left ventricular hypertrophy. Feline HCM closely resembles human HCM and is suggested as translational animal model for the human disease. A genetic cause is established in humans and suspected for cats, but little is known about the gene expression and pathways involved in the pathogenesis of HCM. To investigate...

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PMID: 36928240
DOI: 10.1371/journal.pone.0283244

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