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Article

Autism spectrum disorder and brain volume link through a set of mTOR-related genes.

Journal of child psychology and psychiatry, and allied disciplines - 1 Jul 2023

Arenella Martina, Mota Nina R, Teunissen Mariel W A, Brunner Han G, Bralten Janita

Abstract excerpt

BACKGROUND: Larger than average head and brain sizes are often observed in individuals with autism spectrum disorders (ASDs). ASD and brain volume are both highly heritable, with multiple genetic variants contributing. However, it is unclear whether ASD and brain volume share any genetic mechanisms. Genes from the mammalian target of rapamycin (mTOR) pathway influence brain volume, and variants are found in rare...

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Identifiers

PMID: 36922714
DOI: 10.1111/jcpp.13783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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