Article
Association of TLR4 and TLR9 gene polymorphisms with cervical HR-HPV infection status in Chinese Han population.
BMC infectious diseases - 13 Mar 2023
Zhang Chunlin, Yang Zhiping, Luo Ping, Li Ting, Wang Sutong, Sun Fenglan, Gong Ping, Mei Bing
Abstract excerpt
BACKGROUND: Toll-like receptors (TLRs) may be involved in the natural history of human papillomavirus (HPV) infection. In our study, we aimed to investigate the association of TLR4 (rs10116253, rs1927911, rs10759931) and TLR9 (rs187084, rs352140) gene polymorphisms with cervical persistent high-risk HPV (HR-HPV) infection, as well as multiple HR-HPV infections. METHODS: A total of 269 study subjects were enrolled...