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Article

Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration

30 Dec 2022

Abstract excerpt

PURPOSE To evaluate associations between rare dysfunctional Complement Factor I ( CFI ) genetic variant status and progression to advanced age-related macular degeneration (AAMD), geographic atrophy (GA) and neovascular disease (NV). DESIGN Prospective, longitudinal study PARTICIPANTS Patients aged 55-80 years at baseline identifying as white with non-advanced AMD in one or both eyes at baseline were included....

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PMID: 36909148
DOI: 10.1016/j.xops.2022.100265

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