Assessing the relationship between single nucleotide polymorphisms in Wingless signaling pathway genes and sella turcica morphology.

doi:10.1111/joa.13855

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Article

Assessing the relationship between single nucleotide polymorphisms in Wingless signaling pathway genes and sella turcica morphology.

Journal of anatomy - 1 Jul 2023

Brancher João Armando, Schuh Rodrigo, Torres Maria Fernanda Pioli, de Melo Teixeira do Brasil Jordanna, Hueb Maria Angélica, Dos Santos Haemmerle Carlos Alexandre, Proff Peter, Alam Mohammad Khursheed, Kirschneck Christian, Küchler Erika Calvano

Abstract excerpt

Sella turcica development involves molecular factors and genes responsible for ossification. It is possible that single nucleotide polymorphisms (SNPs) in key genes are involved in morphological variation of sella turcica. Genes belonging to the WNT signaling pathway are involved in the ossification process and are candidates of sella turcica morphology. This study aimed to evaluate if SNPs in WNT6 (rs6754599)...

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PMID: 36898853
DOI: 10.1111/joa.13855
PMCID: PMC10273339

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