Article
Mendelian randomization analysis suggests no associations of herpes simplex virus infections with systemic lupus erythematosus.
Journal of medical virology - 1 Mar 2023
Chang Min-Jing, Liu Meng-Ting, Chen Miao-Ran, Li Nan, Zhao Yu-Hui, Zhang Sheng-Xiao, He Pei-Feng, Yu Qi
Abstract excerpt
Systemic lupus erythematosus (SLE) characterized by immune dysfunction is possibly more vulnerable to herpes simplex virus (HSV) infection. The infection has been intensively considered a common onset and exacerbation of SLE. This study is aimed at elucidating the causal association between SLE and HSV. A bidirectional two-sample Mendelian Randomization (TSMR) analysis was systematically conducted to explore the...
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