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Article

Gene expression changes in subcutaneous adipose tissue due to Cushing's disease

6 Jul 2015

Abstract excerpt

Glucocorticoids have major effects on adipose tissue metabolism. To study tissue mRNA expression changes induced by chronic elevated endogenous glucocorticoids, we performed RNA sequencing on the subcutaneous adipose tissue from patients with Cushing's disease (n=5) compared to patients with nonfunctioning pituitary adenomas (n=11). We found a higher expression of transcripts involved in several metabolic...

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PMID: 26150553
DOI: 10.1530/jme-15-0119

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