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Article

Next-generation sequencing analysis of hepatitis C virus resistance-associated substitutions in direct-acting antiviral failure in South Korea.

Clinical and molecular hepatology - 1 Apr 2023

Kim Kyung-Ah, Lee Sejoon, Park Hye Jung, Jang Eun Sun, Lee Youn Jae, Cho Sung Bum, Kim Young Suk, Kim In Hee, Lee Byung Seok, Chung Woo Jin, Ahn Sang Hoon, Kim Seungtaek, Jeong Sook Hyang

Abstract excerpt

BACKGROUND/AIMS: We used next-generation sequencing (NGS) to analyze resistance-associated substitutions (RASs) and retreatment outcomes in patients with chronic hepatitis C virus (HCV) infection who failed direct-acting antiviral agent (DAA) treatment in South Korea. METHODS: Using prospectively collected data from the Korean HCV cohort study, we recruited 36 patients who failed DAA treatment in 10 centers...

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Share to Antiviral Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Therapy, Combination

Share to Hepatitis C

Share to Hepatitis C, Chronic

Share to Ribavirin

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Identifiers

PMID: 36880209
DOI: 10.3350/cmh.2022.0345
PMCID: PMC10121280

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