Article
New therapies for clear cell ovarian carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 6 Mar 2023
Stewart James, Cunningham Niamh, Banerjee Susana
Abstract excerpt
Ovarian clear cell carcinoma is a rare subtype of epithelial ovarian cancer with unique clinicopathological features. The most common genetic aberration observed is loss of function ARID1A mutations. Advanced and recurrent ovarian clear cell carcinoma is characterized by resistance to standard-of-care cytotoxic chemotherapy and a poor prognosis. Despite the distinct molecular features of ovarian clear cell...
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