From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disorder with the majority of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved. Though sAD is argued to be a polygenic disorder, apolipoprotein E (APOE) ε4, was found three decades ago to pose the strongest genetic risk for sAD. Currently, the only clinically approved disease-modifying drugs for AD are aducanumab...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Attention Deficit Hyperactivity Disorder
• Share to Bipolar Disorder and Treatment
• Share to Genetics and Neurodevelopmental Disorders