Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology.

Bioscience reports - 1 Jan 2000

Caricasole A, Bakker A, Copani A, Nicoletti F, Gaviraghi G, Terstappen G C

Abstract excerpt

Wnts function through the activation of at least three intracellular signal transduction pathways, of which the canonical beta-catenin mediated pathway is the best understood. Aberrant canonical Wnt signaling has been involved in both neurodegeneration and cancer. An impairment of Wnt signals appears to be associated with aspects of neurodegenerative pathologies while overactivation of Wnt signaling is a common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Brain Neoplasms
Share to Cell Adhesion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Central Nervous System Neoplasms

Share to Cytoskeleton

Share to Models, Chemical

Share to Neurodegenerative Diseases

Share to Wnt Proteins

Source

Identifiers

PMID: 16307379
DOI: 10.1007/s10540-005-2893-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology.PMID 16307379Read ↗

Wnt signaling in the nervous system and in Alzheimer's diseaseSemantic proximity Read ↗

The ups and downs of Wnt signaling in prevalent neurological disorders.Semantic proximity Read ↗

Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s diseaseSemantic proximity Read ↗

Wnt Signaling: Role in Alzheimer Disease and SchizophreniaSemantic proximity Read ↗

Harmony of Wnt pathway in Alzheimer's: Navigating the multidimensional progression from preclinical to clinical stagesSemantic proximity Read ↗

Age- and Sex-Associated Wnt Signaling Dysregulation is Exacerbated from the Early Stages of Neuropathology in an Alzheimer’s Disease ModelSemantic proximity Read ↗

Impaired Wnt Signaling in the Prefrontal Cortex of Alzheimer’s DiseaseSemantic proximity Read ↗

Riluzole: a therapeutic strategy in Alzheimer’s disease by targeting the WNT/β-catenin pathwaySemantic proximity Read ↗

The transcriptional landscape of Alzheimer’s disease and its association with Wnt signaling pathwaySemantic proximity Read ↗

The Wnt/β-Catenin Signaling Pathway as a Target in Drug DiscoverySemantic proximity Read ↗

WNT Signaling in NeuroblastomaSemantic proximity Read ↗

Unwinding the role of Wnt signaling cascade and molecular triggers of motor neuron degeneration in amyotrophic lateral sclerosis (ALS)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.