Article
PrismEXP: gene annotation prediction from stratified gene-gene co-expression matrices.
PeerJ - 1 Jan 2023
Lachmann Alexander, Rizzo Kaeli A, Bartal Alon, Jeon Minji, Clarke Daniel J B, Ma'ayan Avi
Abstract excerpt
Background: Gene-gene co-expression correlations measured by mRNA-sequencing (RNA-seq) can be used to predict gene annotations based on the co-variance structure within these data. In our prior work, we showed that uniformly aligned RNA-seq co-expression data from thousands of diverse studies is highly predictive of both gene annotations and protein-protein interactions. However, the performance of the...
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