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Article

Charge-changing point mutations in the E protein of tick-borne encephalitis virus.

Archives of virology - 5 Mar 2023

Kozlovskaya Liubov I, Osolodkin Dmitry I, Tuchynskaya Ksenia K, Shevtsova Anastasia S, Okhezin Egor V, Palyulin Vladimir A, Nikitin Nikolai A, Karganova Galina G

Abstract excerpt

Introduction of point mutations is one of the forces enabling arboviruses to rapidly adapt in a changing environment. The influence of these mutations on the properties of the virus is not always obvious. In this study, we attempted to clarify this influence using an in silico approach. Using molecular dynamics (MD) simulations, we investigated how the position of charge-changing point mutations influences the...

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PMID: 36871232
DOI: 10.1007/s00705-023-05728-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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