Article
Lesion Shedding Model: unraveling site-specific contributions to ctDNA.
Briefings in bioinformatics - 19 Mar 2023
Rhrissorrakrai Kahn, Utro Filippo, Levovitz Chaya, Parida Laxmi
Abstract excerpt
Sampling circulating tumor DNA (ctDNA) using liquid biopsies offers clinically important benefits for monitoring cancer progression. A single ctDNA sample represents a mixture of shed tumor DNA from all known and unknown lesions within a patient. Although shedding levels have been suggested to hold the key to identifying targetable lesions and uncovering treatment resistance mechanisms, the amount of DNA shed by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.