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Article

Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease.

Journal of cachexia, sarcopenia and muscle - 1 Apr 2023

Attaway Amy H, Bellar Annette, Welch Nicole, Sekar Jinendiran, Kumar Avinash, Mishra Saurabh, Hatipoğlu Umur, McDonald Merry-Lynn, Regan Elizabeth A, Smith Jonathan D, Washko George, Estépar Raúl San José, Bazeley Peter, Zein Joe, Dasarathy Srinivasan

Abstract excerpt

BACKGROUND: Sarcopenia, or loss of skeletal muscle mass and decreased contractile strength, contributes to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). The severity of sarcopenia in COPD is variable, and there are limited data to explain phenotype heterogeneity. Others have shown that COPD patients with sarcopenia have several hallmarks of cellular senescence, a potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36856146
DOI: 10.1002/jcsm.13198
PMCID: PMC10067501

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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