Article
Muscle loss phenotype in COPD is associated with adverse outcomes in the UK Biobank.
BMC pulmonary medicine - 17 Apr 2024
Attaway Amy H, Lopez Rocio, Welch Nicole, Bellar Annette, Hatipoğlu Umur, Zein Joe, Engelen Marielle Pkj, Dasarathy Srinivasan
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder with systemic consequences that can cause a muscle loss phenotype (MLP), which is characterized by the loss of muscle mass, muscle strength, or loss of both muscle and fat mass. There are limited data comparing the individual traits of MLP with clinical outcomes in a large unbiased cohort of COPD patients. Our aim was to...
Topics
- Humans
- Male
- Female
- Retrospective Studies
- Hand Strength
- UK Biobank
- Biological Specimen Banks
- Pulmonary Disease, Chronic Obstructive
- Muscle, Skeletal
- Phenotype