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Article

Association of Physical Frailty With Incidence and Life Expectancy of COPD: A Population-Based Cohort Study.

Chest - 1 Oct 2025

Liu Chao, Xiong Hui, Han Xia, Lv Yanling, Wang Decai, Hu Jiannan, Li Ziling, Ma Xinyue, Zhu Yunfei, Xu Shuyun, Chen Liangkai

Abstract excerpt

BACKGROUND: The bidirectional relationship between frailty and COPD is documented. However, longitudinal studies examining the combined effects of genetic predisposition and preserved ratio impaired spirometry (PRISm) on frailty in COPD development are lacking. RESEARCH QUESTION: What is the association between physical frailty and the incidence and mortality of COPD, and how do genetic predisposition and PRISm...

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Identifiers

PMID: 40258513
DOI: 10.1016/j.chest.2025.03.032
PMCID: PMC12597428

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