Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Impact of Highly Effective Cystic Fibrosis Transmembrane Conductance Regulator Modulators on the Health of Female Subjects With Cystic Fibrosis.

Clinical therapeutics - 1 Mar 2023

Taylor-Cousar Jennifer L, Shteinberg Michal, Cohen-Cymberknoh Malena, Jain Raksha

Abstract excerpt

Cystic fibrosis (CF) is a genetic disorder that occurs in people of all genetic ancestries. CF is caused by variants in the CF transmembrane conductance regulator (CFTR) gene that result in decreased, absent, or nonfunctional CFTR protein at the cell surface of the mucous membranes. Clinical manifestations include chronic respiratory disease, malabsorption, and decreased fertility. Historically, therapies for CF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminophenols
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Mutation

Share to Quinolones

Source

Identifiers

PMID: 36841738
DOI: 10.1016/j.clinthera.2023.01.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Impact of Highly Effective Cystic Fibrosis Transmembrane Conductance Regulator Modulators on the Health of Female Subjects With Cystic Fibrosis.PMID 36841738Read ↗

CFTR Modulators: Impact on Fertility, Pregnancy, and Lactation in Women with Cystic FibrosisSemantic proximity Read ↗

Cystic Fibrosis: Highly Effective Targeted Therapeutics and the Impact on Sex and Racial Disparities.Semantic proximity Read ↗

Understanding and addressing the needs of people with cystic fibrosis in the era of CFTR modulator therapy.Semantic proximity Read ↗

Current state of CFTR modulators for treatment of Cystic Fibrosis.Semantic proximity Read ↗

Pregnancy in cystic fibrosis: Review of the literature and expert recommendationsSemantic proximity Read ↗

Considerations for early life genetic therapies in cystic fibrosis.Semantic proximity Read ↗

The ageing of people living with cystic fibrosis: what to expect now?Semantic proximity Read ↗

Update on Clinical Outcomes of Highly Effective Modulator Therapy.Semantic proximity Read ↗

CFTR modulator therapy: transforming the landscape of clinical care in cystic fibrosis.Semantic proximity Read ↗

Pregnancy in Cystic Fibrosis: Review of the Literature and Expert RecommendationsSemantic proximity Read ↗

"Shifting sands in cystic fibrosis": impacts of CFTR modulators on reproductive health in people with cystic fibrosis and challenges related to in utero exposure.Semantic proximity Read ↗

Unmet challenges in cystic fibrosis treatment with modulators.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.