Article
"Shifting sands in cystic fibrosis": impacts of CFTR modulators on reproductive health in people with cystic fibrosis and challenges related to in utero exposure.
Expert opinion on pharmacotherapy - 1 Dec 2024
Felton Imogen, Downes Amy, Bokobza Idan, Weitnauer Ladina, Davies Jane C
Abstract excerpt
INTRODUCTION: Mutation-specific disease modifying drugs such as the triple combination Elexacaftor/Tezacaftor/Ivacaftor (ETI), are associated with significant improvements in physical health. Reproductive health and a pursuit of parenthood are of increased relevance; a dramatic increase in childbirth rates for females with CF has already been observed. AREAS COVERED: Fertility in males and females with CF, and...
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