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The Contribution of the Sheep and the Goat Model to the Study of Ovarian Ageing

8 Feb 2023

Abstract excerpt

Ovarian ageing stands as the major contributor towards fertility loss. As such, there is an urge for studies addressing the mechanisms that promote ovarian ageing and new strategies aiming to delay it. Recently, the presence of a unique population of multinucleated giant cells has been identified in the ovaries of reproductively aged mice. These cells have been considered hallmarks of ovarian ageing. However, up...

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PMID: 36829547
DOI: 10.3390/biology12020270

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