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Article

Molecular Landscape and Association With Crohn Disease of Poorly Cohesive Carcinomas of the Nonampullary Small Bowel.

American journal of clinical pathology - 4 Apr 2023

Tedaldi Gianluca, Guerini Camilla, Angeli Davide, Furlan Daniela, Libera Laura, Lenti Marco Vincenzo, Grillo Federica, Fassan Matteo, Solcia Enrico, Sessa Fausto, Paulli Marco, Di Sabatino Antonio, Ulivi Paola, Vanoli Alessandro

Abstract excerpt

OBJECTIVES: Poorly cohesive carcinomas (PCCs) are neoplasms defined by a predominantly dyshesive growth pattern with single cell or cord-like stromal infiltration. The -distinctive clinicopathologic and prognostic features of small bowel PCCs (SB-PCCs) in comparison with conventional-type small intestinal adenocarcinomas have only recently been characterized. However, as SB-PCCs' genetic profile is still unknown,...

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PMID: 36812376
DOI: 10.1093/ajcp/aqac161
PMCID: PMC10071142

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