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Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies

1 Jan 2016

Abstract excerpt

Cancer stem cells (CSCs) are a unique subset of cells within tumors with stemlike properties that have been proposed to be key drivers of tumor initiation and progression. CSCs are functionally defined by their unlimited self-renewal capacity and their ability to initiate tumor formation in vivo. Like normal stem cells, CSCs exist in a cellular niche comprised of numerous cell types including tumor-associated...

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PMID: 26980947
DOI: 10.1155/2016/9012369

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