Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease

20 Feb 2023

Abstract excerpt

Dysregulated maternal fatty acid metabolism increases the risk of congenital heart disease (CHD) in offspring with an unknown mechanism, and the effect of folic acid fortification in preventing CHD is controversial. Using gas chromatography coupled to either a flame ionization detector or mass spectrometer (GC-FID/MS) analysis, we find that the palmitic acid (PA) concentration increases significantly in serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Congenital Heart Disease Studies
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36809766
DOI: 10.1016/j.xcrm.2023.100953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart diseasePMID 36809766Read ↗

Folic acid supplementation in pregnancy: are there devils in the detail?Semantic proximity Read ↗

Maternal folic acid over-supplementation impairs cardiac function in mice offspring by inhibiting SOD1 expressionSemantic proximity Read ↗

Exploring the Role of Maternal Nutritional Epigenetics in Congenital Heart DiseaseSemantic proximity Read ↗

Environmental Exposures and Congenital Heart DiseaseSemantic proximity Read ↗

Congenital Heart Disease and Genetic Changes in Folate/Methionine Cycles.Semantic proximity Read ↗

Folate, Homocysteine and the Cardiac Neural CrestSemantic proximity Read ↗

Protective and sex‐specific effects of moderate dose folic acid supplementation on the placenta following assisted reproduction in miceSemantic proximity Read ↗

Palmitic acid impairs human and mouse placental function by inhibiting trophoblast autophagy through induction of acyl-coenzyme A-binding protein (ACBP) upregulationSemantic proximity Read ↗

Maternal Serum Folate During Pregnancy and Congenital Heart Disease in OffspringSemantic proximity Read ↗

The Heart-Placenta Axis in the First Month of Pregnancy: Induction and Prevention of Cardiovascular Birth DefectsSemantic proximity Read ↗

Maternal iron deficiency perturbs embryonic cardiovascular developmentSemantic proximity Read ↗

Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.