Article
Autosomal recessive inheritance of goiter in Dutch goats.
The Journal of heredity - 1 Jan 2000
Kok K, van Dijk J E, Sterk A, Baas F, van Ommen G J, de Vijlder J J
Abstract excerpt
The inheritance of congenital goiter due to a thyroglobulin synthesis defect in a strain of Dutch goats has been studied by Mendelian and biochemical methods. Mendelian analysis of 301 matings, resulting in 591 kids, showed an autosomal recessive mode of inheritance. A restriction fragment length polymorphism (RFLP) in the thyroglobulin gene also was used to confirm the recessive mode of inheritance of the...
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