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A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development

13 Feb 2023

Abstract excerpt

Enteric nervous system development relies on intestinal colonization by enteric neural crest-derived cells (ENCDCs). This is driven by a population of highly migratory and proliferative ENCDCs at the wavefront, but the molecular characteristics of these cells are unknown. ENCDCs from the wavefront and the trailing region were isolated and subjected to RNA-seq. Wavefront-ENCDCs were transcriptionally distinct from...

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Share to Congenital gastrointestinal and neural anomalies
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PMID: 36779913
DOI: 10.1242/dev.201090

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