SNPD-CRISPR: Single Nucleotide Polymorphism-Distinguishable Repression or Enhancement of a Target Gene Expression by CRISPR System.

doi:10.1007/978-1-0716-3016-7_4

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Article

SNPD-CRISPR: Single Nucleotide Polymorphism-Distinguishable Repression or Enhancement of a Target Gene Expression by CRISPR System.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023

Maruyama Shohei, Kusakabe Takashi, Zou Xinyi, Kobayashi Yoshiaki, Asano Yoshimasa, Wang Qingbo S, Ui-Tei Kumiko

Abstract excerpt

A wide range of diseases, including cancer, autoimmune diseases, or neurodegenerative diseases, have been associated with single nucleotide mutations in their causative genes. Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system is a flexible and efficient genome engineering technology widely used for researches and therapeutic applications which offers...

Topics

CRISPR-Cas Systems
Polymorphism, Single Nucleotide
RNA
Nucleotides
Gene Expression

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PMID: 36773137
DOI: 10.1007/978-1-0716-3016-7_4

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