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Article

Association of the Telomerase Reverse Transcriptase rs10069690 Polymorphism with the Risk, Age at Onset and Prognosis of Triple Negative Breast Cancer.

International journal of molecular sciences - 17 Jan 2023

Zins Karin, Peka Elisabeth, Miedl Heidi, Ecker Stefanie, Abraham Dietmar, Schreiber Martin

Abstract excerpt

Telomerase reverse transcriptase (TERT) plays a key role in the maintenance of telomere DNA length. The rs10069690 single nucleotide variant, located in intron 4 of TERT, was found to be associated with telomere length and the risk of estrogen receptor-negative but not-positive breast cancer. This study aimed at analysis of the association of rs10069690 genotype and TERT expression with the risk, age at onset,...

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Source

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Identifiers

PMID: 36768147
DOI: 10.3390/ijms24031825
PMCID: PMC9916321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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