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Integration of single sample and population analysis for understanding immune evasion mechanisms of lung cancer

10 Feb 2023

Abstract excerpt

A deep understanding of the complex interaction mechanism between the various cellular components in tumor microenvironment (TME) of lung adenocarcinoma (LUAD) is a prerequisite for understanding its drug resistance, recurrence, and metastasis. In this study, we proposed two complementary computational frameworks for integrating multi-source and multi-omics data, namely ImmuCycReg framework (single sample level)...

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PMID: 36765073
DOI: 10.1038/s41540-023-00267-8

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