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Article

A novel assay for improved detection of sputum periostin in patients with asthma.

PloS one - 1 Jan 2023

Ono Junya, Takai Masayuki, Kamei Ayami, Ohta Shoichiro, Nair Parameswaran, Izuhara Kenji, Dahlén Sven-Erik, James Anna

Abstract excerpt

BACKGROUND: Serum periostin associates with type-2 inflammation in asthmatic airways, but also reflects whole body periostin levels originating from multiple sources. Less is known about sputum periostin as a biomarker in asthma as detection levels are low using currently available periostin assays. We aimed to investigate detection of sputum periostin using ELISA assays targeting different periostin epitopes and...

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Identifiers

PMID: 36763690
DOI: 10.1371/journal.pone.0281356
PMCID: PMC9916630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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