Article
Phenotype of asthma related with high serum periostin levels.
Allergology international : official journal of the Japanese Society of Allergology - 1 Apr 2015
Matsusaka Masako, Kabata Hiroki, Fukunaga Koichi, Suzuki Yusuke, Masaki Katsunori, Mochimaru Takao, Sakamaki Fumio, Oyamada Yoshitaka, Inoue Takashi, Oguma Tsuyoshi, Sayama Koichi, Koh Hidefumi, Nakamura Morio, Umeda Akira, Ono Junya, Ohta Shoichiro, Izuhara Kenji, Asano Koichiro, Betsuyaku Tomoko
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease composed of various phenotypes. Periostin, a molecule inducible with interleukin (IL)-4 or IL-13 in bronchial epithelial cells, is a biomarker of "TH2-high" asthma. The objective of this study is to examine whether the serum periostin concentrations are correlated with the severity, specific phenotype(s), or comorbidity of asthma. METHODS: Serum concentrations of...
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