Article
Periostin levels and eosinophilic inflammation in poorly-controlled asthma.
BMC pulmonary medicine - 30 Apr 2016
Simpson Jodie L, Yang Ian A, Upham John W, Reynolds Paul N, Hodge Sandra, James Alan L, Jenkins Christine, Peters Matthew J, Jia Guiquan, Holweg Cecile T J, Gibson Peter G
Abstract excerpt
BACKGROUND: Periostin levels are associated with airway eosinophilia and are suppressed by corticosteroid treatment in asthma. This study sought to determine the relationship between serum and sputum periostin, airway inflammatory phenotype and asthma control. METHODS: Adults with poorly-controlled asthma (n = 83) underwent a clinical assessment, sputum induction and blood sampling. Dispersed sputum was used for...
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