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Article

BRAF V600E Mutations Occur in a Subset of Glomus Tumors, and Are Associated With Malignant Histologic Characteristics.

The American journal of surgical pathology - 1 Nov 2017

Karamzadeh Dashti Nooshin, Bahrami Armita, Lee Seung J, Jenkins Sarah M, Rodriguez Fausto J, Folpe Andrew L, Boland Jennifer M

Abstract excerpt

Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior. We recently encountered a malignant glomus tumor with BRAF V600E mutation. We sought to study a large cohort for this mutation, with particular attention to associated malignant histologic...

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Identifiers

PMID: 28834810
DOI: 10.1097/PAS.0000000000000913

Genes

BRAF

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