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Article

EGF receptor modulates HEV entry in human hepatocytes

6 Feb 2023

Abstract excerpt

BACKGROUND AND AIMS: Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden. Although the entry process of viral particles is an attractive target for pharmacological intervention, druggable host factors to restrict HEV entry have not been identified so far. APPROACH AND RESULTS: Here we...

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PMID: 36745934
DOI: 10.1097/hep.0000000000000308

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