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RT-RPA-Cas12a-based assay facilitates the discrimination of SARS-CoV-2 variants of concern

26 Jan 2023

Abstract excerpt

Timely and accurate detection of SARS-CoV-2 variants of concern (VOCs) is urgently needed for pandemic surveillance and control. Great efforts have been made from a mass of scientists in increasing the detection sensitivity and operability, and reducing the turn-around time and cost. Here, we report a nucleic acid testing-based method aiming to detect and discriminate SARS-CoV-2 mutations by combining RT-RPA and...

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PMID: 36743821
DOI: 10.1016/j.snb.2023.133433

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