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Article

Meta-analysis of the prevalence of Leber hereditary optic neuropathy mtDNA mutations in Europe.

European journal of ophthalmology - 1 Jan 2000

Mascialino Barbara, Leinonen Mika, Meier Thomas

Abstract excerpt

PURPOSE: A meta-analysis was conducted to estimate the prevalence of patients with molecularly confirmed Leber hereditary optic neuropathy (LHON) carrying any of the 3 primary mtDNA mutations (m.11778G>A, m.14484T>C, m.3460G>A) which cause this inherited form of blindness. METHODS: A literature search was conducted to identify primary reports with LHON prevalence data reported for Europe. The overall prevalence...

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Identifiers

PMID: 21928272
DOI: 10.5301/ejo.5000055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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