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Mapping the tumor microenvironment in bladder cancer and exploring the prognostic genes by single-cell RNA sequencing

19 Jan 2023

Abstract excerpt

Despite substantial advances in the treatment using immune checkpoint inhibitors (ICIs), the clinical expected therapeutic effect on bladder cancer has not been achieved, in which the tumor microenvironment (TME) occupies a notable position. In this research, 10X single-cell RNA-sequencing technology was conducted to analyze seven primary bladder tumor tissues (three non-muscle-invasive bladder cancer (NMIBC) and...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 36741702
DOI: 10.3389/fonc.2022.1105026

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