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Intraluminal chloride regulates lung branching morphogenesis: involvement of PIEZO1/PIEZO2

5 Feb 2023

Abstract excerpt

Abstract Background Clinical and experimental evidence shows lung fluid volume as a modulator of fetal lung growth with important value in treating fetal lung hypoplasia. Thus, understanding the mechanisms underlying these morphological dynamics has been the topic of multiple investigations with, however, limited results, partially due to the difficulty of capturing or recapitulating these movements in the lab....

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PMID: 36740669
DOI: 10.1186/s12931-023-02328-2

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