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Article

Single‐cell transcriptomic survey of cell diversity and functional changes in yak hearts at different altitude

5 Feb 2023

Abstract excerpt

The yak (Bos grunniens) is a species adapted to the hypoxic environment in the plateau area. The heart is a hypoxia-sensitive organ involved in this adaptation. Herein, we used single-cell RNA-seq technology and clustering to determine the presence of 11 cell populations in the yak heart. We analyzed gene expression differences and expression patterns in each cell subpopulation at different altitudes. The cells...

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PMID: 36739517
DOI: 10.1002/pmic.202200345

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