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[Report of Multidisciplinary Treatment for Sisters with Li-Fraumeni Syndrome].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Dec 2022

Suzuki Okihide, Amano Kunihiko, Chika Noriyasu, Yamano Takafumi, Eguchi Hidetaka, Nakashima Hideo, Ooya Soichi, Okazaki Yasushi, Mochiki Erito, Takahashi Takeo, Ishida Hideyuki

Abstract excerpt

Li-Fraumeni syndrome(LFS)is a hereditary cancer disorder caused by germline variant in TP53 and characterized by various malignancies. Multidisciplinary treatment is needed for tumors of LFS, however, radiation therapy is a relative contraindication because of frequent development of secondary malignancy such as sarcoma in the irradiated field. Case 1: A 22- year-old woman who was diagnosed with LFS by genetic...

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PMID: 36733053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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