Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Report of 2 Pediatric Cases With Li-Fraumeni Syndrome Related Malignancy in a Family.

Journal of pediatric hematology/oncology - 1 May 2021

Takeoka Mami, Toyoda Hidemi, Hirayama Junya, Suzuki Naofumi, Hanaki Ryo, Amano Keishiro, Iwamoto Shotaro, Hirayama Masahiro

Abstract excerpt

Li-Fraumeni syndrome (LFS) is a rare inherited disease characterized by a high and early-onset cancer risk. A cancer surveillance program is important to reduce cancer-related morbidity and mortality in individuals with LFS. We report 2 pediatric cases with LFS-related malignancy in a family. Eight-year-old elder brother was diagnosed with adrenocortical carcinoma and was found to have a heterozygous missense...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Rhabdomyosarcoma
Share to Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Adrenal Cortex Neoplasms

Share to Adrenocortical Carcinoma

Share to Child, Preschool

Share to Germ-Line Mutation

Share to Li-Fraumeni Syndrome

Share to Pedigree

Source

Identifiers

PMID: 32555031
DOI: 10.1097/MPH.0000000000001862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Report of 2 Pediatric Cases With Li-Fraumeni Syndrome Related Malignancy in a Family.PMID 32555031Read ↗

[A rhabdomyosarcoma patient from a Li-Fraumeni syndrome family: a case report and literature review].Semantic proximity Read ↗

Li-Fraumeni and Li-Fraumeni-like syndrome among children diagnosed with pediatric cancer in Southern Brazil.Semantic proximity Read ↗

Li–Fraumeni SyndromeSemantic proximity Read ↗

Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers.Semantic proximity Read ↗

Pediatric cancer and Li-Fraumeni/Li-Fraumeni-like syndromes: a review for the pediatrician.Semantic proximity Read ↗

Update on Cancer Screening Recommendations for Individuals with Li–Fraumeni SyndromeSemantic proximity Read ↗

The Li-Fraumeni syndrome.Semantic proximity Read ↗

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome.Semantic proximity Read ↗

Risks of first and subsequent cancers among TP53 mutation carriers in the National Cancer Institute Li-Fraumeni syndrome cohort.Semantic proximity Read ↗

Tumor Spectrum and Temporal Cancer Trends in adult carriers of Li-Fraumeni syndrome: Implications for Personalized Screening Strategies in<i>TP53</i>R337H carriersSemantic proximity Read ↗

p53 Tetramerization domain mutations: germline R342X and R342P, and somatic R337G identified in pediatric patients with Li-Fraumeni syndrome and a child with adrenocortical carcinoma.Semantic proximity Read ↗

The benefit and burden of cancer screening in Li-Fraumeni syndrome: a case report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.