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Article

Loss of dyskerin facilitates the acquisition of metastatic traits by altering the mevalonate pathway.

Life science alliance - 1 Apr 2023

Andrades Evelyn, Toll Agustí, Deza Gustavo, Segura Sonia, Gimeno Ramón, Espadas Guadalupe, Sabidó Eduard, Haro Noemí, Pozo Óscar J, Bódalo Marta, Torres Paloma, Pujol Ramon M, Hernández-Muñoz Inmaculada

Abstract excerpt

The initial dissemination of cancer cells from many primary tumors implies intravasation to lymphatic nodes or blood vessels. To investigate the mechanisms involved, we analyzed the expression of small non-coding RNAs in cutaneous squamous cell carcinoma (cSCC), a prevalent tumor that mainly spreads to lymph nodes. We report the reduced expression of small nucleolar RNAs in primary cSCCs that metastasized when...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36732018
DOI: 10.26508/lsa.202201692
PMCID: PMC9899484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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