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Article

NOTCH4 Single-Nucleotide Polymorphism Is Associated with Brain Arteriovenous Malformation in a Chinese Han Population.

European neurology - 1 Jan 2023

Zhong Ming, Zhang Jianbo, Li Zhenjun, Liu Ziying, Fan Haiyan, Su Hengxian, Meng Hongliang, Zhang Xin, Li Xifeng, Duan Chuan-Zhi, He Xuying

Abstract excerpt

INTRODUCTION: Brain arteriovenous malformations (BAVMs) are high-flow intracranial vascular malformations characterized by the direct connection of arteries to veins without an intervening capillary bed. They are one of the main causes of intracranial hemorrhage and epilepsy, although morbidity is low. Angiogenesis, heredity, inflammation, and arteriovenous malformation syndromes play important roles in BAVM...

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PMID: 36724752
DOI: 10.1159/000526434

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