Article
EPHB4 gene polymorphisms and risk of intracranial hemorrhage in patients with brain arteriovenous malformations.
Circulation. Cardiovascular genetics - 1 Oct 2009
Weinsheimer Shantel, Kim Helen, Pawlikowska Ludmila, Chen Yongmei, Lawton Michael T, Sidney Stephen, Kwok Pui-Yan, McCulloch Charles E, Young William L
Abstract excerpt
BACKGROUND: Brain arteriovenous malformations (BAVMs) are a tangle of abnormal vessels directly shunting blood from the arterial to venous circulation and an important cause of intracranial hemorrhage (ICH). EphB4 is involved in arterial-venous determination during embryogenesis; altered signalin...
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