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Article

Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2011

Mikhak Bahar, Weinsheimer Shantel, Pawlikowska Ludmila, Poon Annie, Kwok Pui-Yan, Lawton Michael T, Chen Yongmei, Zaroff Jonathan G, Sidney Stephen, McCulloch Charles E, Young William L, Kim Helen

Abstract excerpt

BACKGROUND: Brain arteriovenous malformations (BAVM) are high-flow vascular lesions prone to intracranial hemorrhage (ICH). Abnormal angiogenesis is a key characteristic of BAVM tissue. Angiopoietin-like 4 (ANGPTL4), a secreted glycoprotein, is thought to be involved in angiogenesis and required for proper postnatal blood vessel partitioning. We investigated whether common single nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 21212665
DOI: 10.1159/000322601
PMCID: PMC3030504

Genes

ANGPTL4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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