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Article

Association of CYP2C19, CYP3A4 and ABCC2 polymorphisms and voriconazole plasma concentrations in Uygur pediatric patients.

Pharmacogenomics - 1 Feb 2023

Zhao Ting, Shen Hao, Zhang Hui-Lan, Feng Jie, Liu Si-Ming, Wang Ting-Ting, Li Hong-Jian, Yu Lu-Hai

Abstract excerpt

Aim: To evaluate the association between CYP2C19, CYP3A4 and ABCC2 polymorphisms and voriconazole plasma concentrations in Uygur pediatric patients with allogeneic hematopoietic stem cell transplantation. Materials & methods: High performance liquid chromatography-mass spectrometry was employed to monitor voriconazole concentrations. First-generation sequencing was performed to detect gene polymorphisms. Results:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36718992
DOI: 10.2217/pgs-2022-0159

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