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Article

Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors.

Nature communications - 7 Apr 2020

Djomehri Sabra I, Gonzalez Maria E, da Veiga Leprevost Felipe, Tekula Shilpa R, Chang Hui-Yin, White Marissa J, Cimino-Mathews Ashley, Burman Boris, Basrur Venkatesha, Argani Pedram, Nesvizhskii Alexey I, Kleer Celina G

Abstract excerpt

Metaplastic breast carcinoma (MBC) is a highly aggressive form of triple-negative cancer (TNBC), defined by the presence of metaplastic components of spindle, squamous, or sarcomatoid histology. The protein profiles underpinning the pathological subtypes and metastatic behavior of MBC are unknown. Using multiplex quantitative tandem mass tag-based proteomics we quantify 5798 proteins in MBC, TNBC, and normal...

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Share to Carcinoma, Ductal, Breast
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Metabolic Networks and Pathways

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Source

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Identifiers

PMID: 32265444
DOI: 10.1038/s41467-020-15283-z
PMCID: PMC7138853

Genes

CCN6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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